Job Requisition:Influenza Laboratory Scientist
The CDC is the US Government’s lead for monitoring and responding to seasonal, novel, and pandemic influenza. The mission of the Influenza Division of the National Center for Immunization and Respiratory Diseases (NCIRD), Office of Infectious Disease (OID) at the CDC is to improve global control and prevention of seasonal and novel influenza and improve pandemic preparedness and response.
Leidos is seeking experienced biological scientists to support the laboratory activities of the Influenza Division of the CDC. Scientists will conduct research and public health evaluation activities to develop and assess new diagnostic methods and improve existing diagnostic methods to allow for more rapid response to potential influenza and other pathogen outbreaks and the development and improvement of vaccines. Scientists will also provide overarching lab support, maintenance, logistics, inventory, and compliance support for the laboratories. Candidates should be comfortable working in a fast paced and dynamic team environment. More experienced scientists will be expected to train junior scientists and lab personnel on techniques, standard operating procedures, and equipment usage. Candidates will be expected to comply with CDC and Leidos requirements for laboratory safety and security. Some travel, both domestic and international, may be required to support certain subtasks by on site staff. This position is contingent upon contract award.
The primary responsibilities of the Influenza Laboratory Scientist may include:
- Develop and support high throughput and point of service diagnostics for analyses of clinical specimens to characterize influenza (and other respiratory illness) infections
- Generate and characterize new inventories of influenza viruses and other respiratory viral, bacterial, and other pathogenic agents for use in developing diagnostics
- Develop and apply novel molecular characterization methods to perform detailed analysis of genes and laboratory surveillance of gene evolution
- Develop new laboratory agents for new diagnostic methods
- Develop new methods and procedures for efficient construction of candidate vaccine viruses
- Update the research program to identify circulating stains of influenza viruses to improve diagnostic methods
- Develop and apply immunologic assays to improve detection of influenza virus infections and vaccine responses.
- Assess drug susceptibility of seasonal and zoonotic influenza viruses
- Characterize epidemic and potentially pandemic influenza virus properties associated with immunity, pathogenesis and transmission in in vivo and in vitro systems
- Evaluate newly developed serological, immunological, and genetic assays for detection of drug-resistant variants among influenza viruses of various types and subtypes
- Identify, characterize, catalog and store circulating strains of animal influenza viruses to monitor influenza virus infections at the animal-human interface
- Develop new and support existing specimen databases and public health reporting systems
- In collaboration with the Influenza Division’s bioinformatics team, support the high-throughput next-generation sequencing pipelines by producing high-quality, influenza genomic data for influenza viral surveillance and control
- Establish and maintain high-throughput automation platforms for immunogenicity evaluation to influenza vaccination and infection
- Support clinical trials and field studies of influenza vaccines
- Conduct laboratory studies leading to new influenza diagnostic, evaluation of innate and adaptive immune responses to influenza vaccination and infection, and testing of novel vaccines and therapeutic interventions against seasonal, novel, and pandemic influenza
- Experienced biological scientist (MS with 5+ years of experience or Ph.D. with 3+ years of experience) with a background in in Biology, Molecular Biology, Microbiology, Biochemistry, Bioinformatics, Cell Biology, Immunology, Virology, Genetics, and/or other related life science backgrounds
- Experience developing protocols, reports, publications, and presentations
- Excellent written and oral communication skills
- Must be able to obtain access to BSL3 enhanced laboratories and animal facilities
- Working knowledge of laboratory and safety regulations including CLIA, ISO, and/or OSHA standards
- Experience working in a BSL 2 laboratory or higher
Track record of scientific publication on topics related to diagnostics and surveillance of infectious disease
External Referral Bonus:Ineligible
Potential for Telework:No
Clearance Level Required:Public Trust
Travel:Yes, 10% of the time
Scheduled Weekly Hours:40
Job Family:Life Scientist2000Health
Leidos is a Fortune 500® information technology, engineering, and science solutions and services leader working to solve the world's toughest challenges in the defense, intelligence, homeland security, civil, and health markets. The company's 33,000 employees support vital missions for government and commercial customers. Headquartered in Reston, Virginia, Leidos reported annual revenues of approximately $10.19 billion for the fiscal year ended December 28, 2018. For more information, visit www.Leidos.com.
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