Bioinformatics Developers

Description

Job Description:

Leidos Public Health Division is seeking several Bioinformatics Developers, contingent upon contract award, to support public health projects.

The ideal candidate will have demonstrated experience in Next Generation Sequencing (NGS) data analysis including development and application of quality control, assembly, functional annotation, sequence alignment, variant detection, and phylogenetic analyses of viral, bacterial, fungal and protist genomes, transcriptomes and metagenomes. Position will primarily telecommute

Responsibilities

Develop, test, and deploy bioinformatics data pipelines and workflows using open source platforms such as Agave, Workflow Description Language, Snakemake, Nextflow and Taverna

Develop and execute bioinformatics algorithms and workflows in high-performance computing environments; including cloud and hybrid-cloud execution environments

Write customs scripts and software to perform bioinformatics analysis using Python, Perl, R and/or Java

Perform bioinformatics analysis using open-source bioinformatics tools as well as licensed proprietary software such as CLC Genomics Workbench and Geneious. Support modeling and simulation of evolutionary and population biological process using Bayesian inference and/or genetic algorithms.

Use statistical analysis tools, interpret and communicate results

Provide support for approaches, processes, and methods for the management, integration, analysis, and visualization of data from disparate data sources.

Develop tools for visualizing complex biological datasets and able to interpret and communicate results as well as uncertainty to a diverse group of customers.

Develop and maintain highly curated genomic sequence databases, signature databases for virulence and AMR markers, strain type and pathogen type markers.

Work together with the DevOps team in adopting best software engineering practices for tool and workflow development.

Adapt bioinformatics algorithms and workflows in high-performance computing environments; including cloud and hybrid-cloud execution environments.

Provide guidance and support in scaled data analysis and management of next generation metagenomic sequencing data.

Assist with developing standard operating procedures for bioinformatics analyses.

Assist in the development and maintenance of specialized, high-performance databases

for different aspects of ‘omics analysis, including: relational databases such as PostgreSQL,

MySQL/MemSQL/MariaDB, and Microsoft SQL Server for data integration; NoSQL-based databases, such as MongoDB, for high-volume, unformatted data sets; and custom, binary databases such as BLASTDB for hardware-accelerated and conventional BLAST searches.

Collaborate with external and internal subject matter experts identified above to develop,

implement, and maintain novel data science analytic workflows and connectivity to various existing data science analytic workflows used for downstream processing of genomic assemblies and relevant metadata. Additionally, this might require the development of internal application programming interfaces (APIs) and API calls to external databases.

Perform statistical analyses using R, Python, and/or other open-source or commercial

statistical applications, as required. The contractor shall work with team members to develop schemes and methods for visualizing complex scientific datasets using Tableau, SpotFire, ggplot, D3, R, Circos, Processing, etc.

Supports researchers in creating and submitting publication and poster presentations.

Communicate progress orally and in writing with our scientific community stakeholders

Assist with preparation of reports, presentations and papers for publication in scientific journals, conferences and meetings

MINIMUM QUALIFICATIONS:

• A Bachelor’s or Master’s degree in bioinformatics, genomics, molecular biology, genetics or related field;
• 1-2 years of bioinformatics experience
• Experience in front-end development for bioinformatics tools, workflows and applications using AngularJS and NodeJS.
• Experience with processing of high-throughput data and possessing strong data management and analysis skills.
• Experience working in Linux environments and broad experience with open source bioinformatics tools
• Proficient in coding/scripting in Python, R, Perl
• Experience working in a high-performance computing and/or cloud computing environment
• Competency writing customs scripts and software to perform bioinformatics analysis using Python, Perl, R and/or Java.
• Strong communication skills
• Ability to obtain NACI clearance.

PREFERRED QUALIFICATIONS:

• Strongly preferred experience in operating and developing components for workflow management systems such as Nextflow, Snakemake, and/or Workflow Description Language (WDL).

• Experience in designing and conducting training workshops to the bioinformatics community on latest bioinformatics methods and concepts.
• Experience with Tableau, Cloudera (Hadoop), JavaScript
• Experience with machine learning approaches
• Experience in designing and conducting training workshops to the bioinformatics community on latest bioinformatics methods and concepts.
• Experience with Tableau, Cloudera (Hadoop), JavaScript
• Experience in one or more of the following phylogenetic analysis and visualization tools is highly desirable: BEAST, FastTree, RaxML, TreeTime, NextStrain, Microreact

Preferred candidate within driving distance to Atlanta to facilitate incidental in person meeting with government researchers and scientists.

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Pay Range:

#Remote

About Leidos

Leidos is a Fortune 500® technology, engineering, and science solutions and services leader working to solve the world’s toughest challenges in the defense, intelligence, civil, and health markets. The company’s 45,000 employees support vital missions for government and commercial customers. Headquartered in Reston, Virginia, Leidos reported annual revenues of approximately $14.4 billion for the fiscal year ended December 30, 2022.  For more information, visit www.Leidos.com.

Pay and Benefits

Pay and benefits are fundamental to any career decision. That's why we craft compensation packages that reflect the importance of the work we do for our customers. Employment benefits include competitive compensation, Health and Wellness programs, Income Protection, Paid Leave and Retirement. More details are available here.

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Commitment to Diversity

All qualified applicants will receive consideration for employment without regard to sex, race, ethnicity, age, national origin, citizenship, religion, physical or mental disability, medical condition, genetic information, pregnancy, family structure, marital status, ancestry, domestic partner status, sexual orientation, gender identity or expression, veteran or military status, or any other basis prohibited by law. Leidos will also consider for employment qualified applicants with criminal histories consistent with relevant laws.